Journal: Journal of Clinical Medicine
Article Title: Early Fever in Allogeneic Stem Cell Transplantation: Are Presepsin and YKL-40 Valuable Diagnostic Tools?
doi: 10.3390/jcm13195991
Figure Lengend Snippet: Serum values of PSP, YKL-40, and PCT during the first seven days after the onset of FE. Values are plotted on a linear scale after natural logarithm transformation due to their wide range, allowing better visualization. ( a ) Differences in median LnPSP concentrations. ( b ) Differences in median LnYKL-40 concentrations. ( c ) Differences in median LnPCT concentrations. Each box-and-whiskers plot (drawn using the Tuckey method) depicts the median value (horizontal line) and the values from the first to third quartile (central box). Each whisker extends from the edges of the box to the smallest and largest values within 1.5 times the interquartile range. Outliers are depicted as circles. Differences in biomarker values between FUO and infection groups were tested using the Mann–Whitney U test. ns = non-significant, * = p < 0.05, ** = p < 0.01. FE, febrile episode; FUO, fever of unknown origin; PCT, procalcitonin; PSP, presepsin.
Article Snippet: The concentration of YKL-40 and PSP was determined on the Tecan Sunrise absorbance reader with Magellan software version 7.3 (Tecan Group A.G., Männedorf, Switzerland).
Techniques: Transformation Assay, Whisker Assay, Biomarker Discovery, Infection, MANN-WHITNEY